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Rbms1tm1Hiro
Targeted Allele Detail
Nomenclature
Symbol: Rbms1tm1Hiro
Name: RNA binding motif, single stranded interacting protein 1; targeted mutation 1, Hiroyoshi Ariga
MGI ID: MGI:2384095
Synonyms: Mssp-
Gene: Rbms1  Location: Chr2:60750193-60963192 bp, - strand  Genetic Position: Chr2, 34.95 cM, cytoband C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77893
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exon 1 with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was confirmed by RT-PCR analysis. Western blot using polyclonal antibodies directed against amino acids 343-370 did not detect protein product in homozygous mutants. (J:77893)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rbms1 Mutation:  40 strains or lines available
References
Original:  J:77893 Fujimoto M, et al., Disruption of MSSP, c-myc single-strand binding protein, leads to embryonic lethality in some homozygous mice. Genes Cells. 2001 Dec;6(12):1067-75
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory