Tg(WT1)WWNdh
Transgene Detail

Summary

• Symbol: Tg(WT1)WWNdh
• Name: transgene insertion WW, Nicholas D Hastie
• MGI ID: MGI:2183656
• Synonyms: WT280^WW
• Transgene: Tg(WT1)WWNdh Location: unknown
• Alliance: Tg(WT1)WWNdh page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(WT1)WWNdh expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  WT1 (7490)

  Wt1	(MGI:98968)

• A 280 kb YAC containing the human gene WT1 was used as the transgene. (J:52756)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

Founders WA and WW carry 1-2 copies of the transgene, and founder WC carries 4-5 copies of the transgene. Founders WC and WW are male sterile.

References

• Original: J:52756 Moore AW, et al., YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. Development. 1999 May;126(9):1845-57
• All: 1 reference(s)