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Runx3tm1Yg
Targeted Allele Detail
Nomenclature
Symbol: Runx3tm1Yg
Name: runt related transcription factor 3; targeted mutation 1, Yoram Groner
MGI ID: MGI:2183399
Synonyms: Runx3-
Gene: Runx3  Location: Chr4:135120652-135177990 bp, + strand  Genetic Position: Chr4, 67.19 cM
Pathological findings in large intestines of Runx3tm1Yg/Runx3tm1Yg and +/+ wild-type.

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77764
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 38 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Runx3 Mutation:  3 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Inflammatory Bowel Disease (J:93240).

References
Original:  J:77764 Levanon D, et al., The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons. EMBO J. 2002 Jul 1;21(13):3454-63
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory