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Targeted Allele Detail
Symbol: Ugt8atm1Pop
Name: UDP galactosyltransferase 8A; targeted mutation 1, Brian Popko
MGI ID: MGI:2183312
Synonyms: Cgt-, Cgt0, CGTnull
Gene: Ugt8a  Location: Chr3:125865271-125938619 bp, - strand  Genetic Position: Chr3, 54.68 cM, cytoband E3-F1
Germline Transmission:  Earliest citation of germline transmission: J:77226
Parent Cell Line:  BK4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsExon 2 was disrupted by the insertion of a neomycin selection cassette 219 base pairs downstream of the translational start codon. Northern blot analyses showed the exclusive presence of truncated transcript containing the neo transgene in homozgous mutant mice. (J:77226)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ugt8a Mutation:  3 strains or lines available
Original:  J:77226 Coetzee T, et al., Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability. Cell. 1996 Jul 26;86(2):209-19
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
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