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Targeted Allele Detail
Symbol: Fancgtm1Ada
Name: Fanconi anemia, complementation group G; targeted mutation 1, Alan D'Andrea
MGI ID: MGI:2183264
Synonyms: Fancg-
Gene: Fancg  Location: Chr4:43002343-43010506 bp, - strand  Genetic Position: Chr4, 22.97 cM, cytoband B1
Germline Transmission:  Earliest citation of germline transmission: J:72945
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S4/SvJae
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExons 2-9 were replaced with an FRT-flanked neo cassette via homologous recombination. The targeting vector introduces stop codons in all 3 reading frames. Gene transcripts were absent in testes from homozygous mutant animals as assayed by RT-PCR analysis using primers to exons 5 and 6. (J:72945)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fancg Mutation:  7 strains or lines available
Original:  J:72945 Yang Y, et al., Targeted disruption of the murine Fanconi anemia gene, Fancg/Xrcc9. Blood. 2001 Dec 1;98(12):3435-40
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.12
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