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Upk3atm1Tsun
Targeted Allele Detail
Nomenclature
Symbol: Upk3atm1Tsun
Name: uroplakin 3A; targeted mutation 1, Tung-Tien Sun
MGI ID: MGI:2183244
Synonyms: UPIII(-)
Gene: Upk3a  Location: Chr15:85017141-85022560 bp, + strand  Genetic Position: Chr15, 40.25 cM, cytoband E3
Urothelium lacks the umbrella cells and is leaky in Upk3atm1Tsun/Upk3atm1Tsun mice

Show the 5 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77653
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Upk3a Mutation:  4 strains or lines available
References
Original:  J:77653 Hu P, et al., Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux. J Cell Biol. 2000 Nov 27;151(5):961-72
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory