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Smpd1tm1Esc
Targeted Allele Detail
Nomenclature
Symbol: Smpd1tm1Esc
Name: sphingomyelin phosphodiesterase 1, acid lysosomal; targeted mutation 1, Edward H Schuchman
MGI ID: MGI:2183206
Synonyms: ASM-, ASMase-, ASMKO, ASMKO-
Gene: Smpd1  Location: Chr7:105554360-105558388 bp, + strand  Genetic Position: Chr7, 55.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:26732
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smpd1 Mutation:  1 strain or line available
References
Original:  J:26732 Horinouchi K, et al., Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease. Nat Genet. 1995 Jul;10(3):288-93
All:  63 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory