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Rev3ltm1Ndew
Targeted Allele Detail
Nomenclature
Symbol: Rev3ltm1Ndew
Name: REV3 like, DNA directed polymerase zeta catalytic subunit; targeted mutation 1, Niels De Wind
MGI ID: MGI:2183197
Synonyms: Rev3-
Gene: Rev3l  Location: Chr10:39732118-39875211 bp, + strand  Genetic Position: Chr10, 21.04 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75450
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 10 kb region of the gene encoding DNA polymerase domains I, II, III, and IV, was replaced with a PGK-hygro cassette by homologous recombination. (J:75450)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rev3l Mutation:  60 strains or lines available
References
Original:  J:75450 Van Sloun PP, et al., Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage. Mol Cell Biol. 2002 Apr;22(7):2159-69
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory