About   Help   FAQ
Galtm1Wyn
Targeted Allele Detail
Nomenclature
Symbol: Galtm1Wyn
Name: galanin and GMAP prepropeptide; targeted mutation 1, David Wynick
MGI ID: MGI:2183172
Synonyms: galanin -, Gal KO, GALKO
Gene: Gal  Location: Chr19:3409915-3414544 bp, - strand  Genetic Position: Chr19, 3.16 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78046
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 through 5 were replaced with a neomycin selection cassette. Protein encoded by the targeted locus was undetected by radioimmunoassays of homozygous mutant brain and peripheral tissues. (J:78046)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 11 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Gal Mutation:  18 strains or lines available
References
Original:  J:78046 Wynick D, et al., Galanin regulates prolactin release and lactotroph proliferation. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12671-6
All:  26 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/07/2020
MGI 6.15
The Jackson Laboratory