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Proctm1Fjc
Targeted Allele Detail
Nomenclature
Symbol: Proctm1Fjc
Name: protein C; targeted mutation 1, Francis J Castellino
MGI ID: MGI:2183063
Synonyms: PC-
Gene: Proc  Location: Chr18:32123129-32139570 bp, - strand  Genetic Position: Chr18, 17.94 cM, cytoband B3
Hemorrhage in F7tm1Pec/F7tm1Pec Proctm1Fjc/Proctm1Fjc embryos at E14.5

Show the 2 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:50527
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 63 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Proc Mutation:  3 strains or lines available
References
Original:  J:50527 Jalbert LR, et al., Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice. J Clin Invest. 1998 Oct 15;102(8):1481-8
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory