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Lgals3tm1Poi
Targeted Allele Detail
Nomenclature
Symbol: Lgals3tm1Poi
Name: lectin, galactose binding, soluble 3; targeted mutation 1, Francoise Poirier
MGI ID: MGI:2183057
Synonyms: GaL3-, galectin 3-
Gene: Lgals3  Location: Chr14:47611317-47623624 bp, + strand  Genetic Position: Chr14, 24.6 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:47227
Parent Cell Line:  WW6 (ES Cell)
Strain of Origin:  STOCK 129/Sv and C57BL/6J and SJL
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details3.7kb of sequence, encompassing exons 2 through 4, was replaced via the insertion of a neomycin selection cassette. Immunostaining of fetal skin showed an absence of protein in homozygous mutant embryos. (J:47227)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 8 assay results
In Structures Affected by this Mutation: 8 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Lgals3 Mutation:  20 strains or lines available
References
Original:  J:47227 Colnot C, et al., Embryonic implantation in galectin 1/galectin 3 double mutant mice. Dev Dyn. 1998 Apr;211(4):306-13
All:  66 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory