Efnb2^tm2Kln
Targeted Allele Detail

Summary

• Symbol: Efnb2^tm2Kln
• Name: ephrin B2; targeted mutation 2, Rudiger Klein
• MGI ID: MGI:2182628
• Synonyms: ephrinB2^wt
• Gene: Efnb2 Location: Chr8:8667434-8711242 bp, - strand Genetic Position: Chr8, 3.42 cM
• Alliance: Efnb2^tm2Kln page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67296
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: This allele was created to generate Efnb2^tm2.1Kln. A modified cDNA of the endogenous locus encoding the full length protein and a hemagglutinin (HA) epitope tag, was inserted immediately downstream of exon 1. The construct also contained a downstream floxed neo gene. (J:67296)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efnb2 Mutation: 27 strains or lines available

References

• Original: J:67296 Adams RH, et al., The cytoplasmic domain of the ligand ephrinB2 is required for vascular morphogenesis but not cranial neural crest migration. Cell. 2001 Jan 12;104(1):57-69
• All: 1 reference(s)