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Fgfr1tm3Cxd
Targeted Allele Detail
Nomenclature
Symbol: Fgfr1tm3Cxd
Name: fibroblast growth factor receptor 1; targeted mutation 3, Chu-Xia Deng
MGI ID: MGI:2181471
Synonyms: Fgfr1neo-Co
Gene: Fgfr1  Location: Chr8:25513654-25575714 bp, + strand  Genetic Position: Chr8, 14.12 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75137
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA single loxP site was introduced 5' to exon 8 and a loxP-flanked neomycin resistance cassette was inserted 3' to exon 14. This mutation interferes with normal spicing of the encoded transcript. (J:75137)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgfr1 Mutation:  171 strains or lines available
References
Original:  J:75137 Xu X, et al., Generation of Fgfr1 conditional knockout mice. Genesis. 2002 Feb;32(2):85-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory