Tg(Camk2a-cre)2Gsc
Transgene Detail

Summary

• Symbol: Tg(Camk2a-cre)2Gsc
• Name: transgene insertion 2, Gunther Schutz
• MGI ID: MGI:2181426
• Synonyms: CamiCre, Camk2a-cre, Camk2a-iCre, Camk^Cre, CamK-Cre, CaMKIIaCre, CamKIIalphaCre, CamKIIalpha-Cre, CamKIIalpha iCre
• Transgene: Tg(Camk2a-cre)2Gsc Location: unknown
• Alliance: Tg(Camk2a-cre)2Gsc page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Camk2a-cre)2Gsc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Camk2a (MGI:88256)

• Mutation details: This BAC insertion expresses an enhanced Cre recombinase and an enhanced green fluorescent protein under the control of a mouse Camk2a promoter. The promoter is active in brain regions including the dentate gyrus, CA1/CA3 regions of the hippocampus, cortex, olfactory bulb, and amygdala, and more weakly active in the striatum, thalamus, and hypothalamus. (J:71980)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Camk2a (mouse) Summary of all recombinase alleles driven by Camk2a. Comparative matrix view of recombinase activities Alliance mouse Camk2a gene page

Disease models

Expression

In Mice Carrying this Mutation:

7 assay results 6 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:71980 Casanova E, et al., A CamKIIalpha iCre BAC allows brain-specific gene inactivation. Genesis. 2001 Sep;31(1):37-42
• All: 161 reference(s)