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Nr1h3tm1Djm
Targeted Allele Detail
Nomenclature
Symbol: Nr1h3tm1Djm
Name: nuclear receptor subfamily 1, group H, member 3; targeted mutation 1, David J Mangelsdorf
MGI ID: MGI:2181380
Synonyms: LXRalpha (-), Nr1h3-
Gene: Nr1h3  Location: Chr2:91184061-91202834 bp, - strand  Genetic Position: Chr2, 50.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:47971
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Nr1h3 Mutation:  10 strains or lines available
References
Original:  J:47971 Peet DJ, et al., Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell. 1998 May 29;93(5):693-704
All:  60 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory