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Arl4atm1Asch
Targeted Allele Detail
Nomenclature
Symbol: Arl4atm1Asch
Name: ADP-ribosylation factor-like 4A; targeted mutation 1, A Schurmann
MGI ID: MGI:2181269
Synonyms: Arl4-
Gene: Arl4a  Location: Chr12:40005447-40038025 bp, - strand  Genetic Position: Chr12, 18.06 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75778
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 of the gene was replaced with a neomycin resistance cassette via homologous recombination. Northern blot analysis confirmed the absence of mRNA transcripts from testis, spleen, and intestine of homozygous mutant animals, and immunohistochemical analysis of testes sections demonstrated the absence of protein product. (J:75778)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arl4a Mutation:  5 strains or lines available
References
Original:  J:75778 Schurmann A, et al., Reduced sperm count and normal fertility in male mice with targeted disruption of the ADP-ribosylation factor-like 4 (Arl4) gene. Mol Cell Biol. 2002 Apr;22(8):2761-8
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory