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Akt1tm1Mbb
Targeted Allele Detail
Nomenclature
Symbol: Akt1tm1Mbb
Name: thymoma viral proto-oncogene 1; targeted mutation 1, Morris J Birnbaum
MGI ID: MGI:2180150
Synonyms: Akt-
Gene: Akt1  Location: Chr12:112653821-112674884 bp, - strand  Genetic Position: Chr12, 61.2 cM, cytoband F1-F2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:72176
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Akt1 Mutation:  10 strains or lines available
References
Original:  J:72176 Cho H, et al., Akt1/pkbalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J Biol Chem. 2001 Oct 19;276(42):38349-52
All:  62 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory