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Tgm1tm1Kfyn
Targeted Allele Detail
Nomenclature
Symbol: Tgm1tm1Kfyn
Name: transglutaminase 1, K polypeptide; targeted mutation 1, Kiyofumi Yamanishi
MGI ID: MGI:2179115
Synonyms: Tgase 1-
Gene: Tgm1  Location: Chr14:55700009-55713492 bp, - strand  Genetic Position: Chr14, 28.19 cM, cytoband C1
Epidermal abnormalities in Tgm1tm1Kfyn/Tgm1tm1Kfyn mice

Show the 4 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:45653
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tgm1 Mutation:  9 strains or lines available
References
Original:  J:45653 Matsuki M, et al., Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase). Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1044-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory