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Targeted Allele Detail
Symbol: Kcnip3tm1Pngr
Name: Kv channel interacting protein 3, calsenilin; targeted mutation 1, Josef M Penninger
MGI ID: MGI:2179103
Synonyms: dream-
Gene: Kcnip3  Location: Chr2:127456498-127522094 bp, - strand  Genetic Position: Chr2, 62.02 cM
Germline Transmission:  Earliest citation of germline transmission: J:74345
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance gene replaced sequences encoding EF hands I and II and the proximal 5' region of this gene (amino acids 58-143.) Northern and Western blot of brain from homozygous mutant animals verified the absence of gene expression. (J:74345)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnip3 Mutation:  17 strains or lines available
Original:  J:74345 Cheng HY, et al., DREAM is a critical transcriptional repressor for pain modulation. Cell. 2002 Jan 11;108(1):31-43
All:  10 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
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