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Targeted Allele Detail
Symbol: Fgf18tm1Dor
Name: fibroblast growth factor 18; targeted mutation 1, David M Ornitz
MGI ID: MGI:2178751
Synonyms: Fgf18-
Gene: Fgf18  Location: Chr11:33117430-33147400 bp, - strand  Genetic Position: Chr11, 19.21 cM
Germline Transmission:  Earliest citation of germline transmission: J:75879
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 1, which codes for the translation initiation site and the signal peptide, was deleted and replaced by a 7kb fragment containing lacZ and a neo cassette. (J:75879)
View phenotypes and curated references for all genotypes (concatenated display).
In Mice Carrying this Mutation: 4 assay results
In Structures Affected by this Mutation: 19 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fgf18 Mutation:  1 strain or line available
Original:  J:75879 Liu Z, et al., Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 2002 Apr 1;16(7):859-69
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory