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F3tm1Dco
Targeted Allele Detail
Nomenclature
Symbol: F3tm1Dco
Name: coagulation factor III; targeted mutation 1, Desire Collen
MGI ID: MGI:2178434
Synonyms: mF3-, mTF-, TF -
Gene: F3  Location: Chr3:121723537-121735048 bp, + strand  Genetic Position: Chr3, 52.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35120
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced the first exon of the gene. Northern blot analysis on embryonic fibroblasts derived from homozygous mice demonstrated that no detectable transcript was expressed from this allele. (J:35120)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any F3 Mutation:  11 strains or lines available
References
Original:  J:35120 Carmeliet P, et al., Role of tissue factor in embryonic blood vessel development. Nature. 1996 Sep 5;383(6595):73-5
All:  31 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory