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Pde6brd1-3H
Chemically induced Allele Detail
Nomenclature
Symbol: Pde6brd1-3H
Name: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; retinal degeneration 1, 3 Harwell
MGI ID: MGI:2178319
Synonyms: Gena362, GENA 362
Gene: Pde6b  Location: Chr5:108388373-108431743 bp, + strand  Genetic Position: Chr5, 53.07 cM
Mutation
origin
Strain of Origin:  (C3H/HeN x BALB/cAnN)F1
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsA nonsense mutation in exon 9 (G1133A) caused a premature stop codon at the tryptophan at amino acid position 378. (J:75964)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pde6b Mutation:  117 strains or lines available
References
Original:  J:75964 Thaung C, et al., Novel ENU-induced eye mutations in the mouse: models for human eye disease. Hum Mol Genet. 2002 Apr 1;11(7):755-67
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory