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Pde6batrd1
Chemically induced Allele Detail
Nomenclature
Symbol: Pde6batrd1
Name: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; atypical retinal degeneration 1
MGI ID: MGI:2178311
Synonyms: Gena245, GENA 245, Pde6bH620Q
Gene: Pde6b  Location: Chr5:108536239-108579609 bp, + strand  Genetic Position: Chr5, 53.07 cM
Mutation
origin
Strain of Origin:  BALB/cAnN
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsA T1860A missense mutation in exon 15 resulted in a histidine to glutamine substitution at amino acid 620. (J:75964)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Pde6b Mutation:  101 strains or lines available
References
Original:  J:75964 Thaung C, et al., Novel ENU-induced eye mutations in the mouse: models for human eye disease. Hum Mol Genet. 2002 Apr 1;11(7):755-67
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory