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Serpinc1tm1Sai
Targeted Allele Detail
Nomenclature
Symbol: Serpinc1tm1Sai
Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1; targeted mutation 1, Hidehiko Saito
MGI ID: MGI:2178128
Synonyms: AT-, ATIII-
Gene: Serpinc1  Location: Chr1:160978606-161003010 bp, + strand  Genetic Position: Chr1, 69.75 cM
Subcutaneous hemorrhage in Serpinc1tm1Sai/Serpinc1tm1Sai mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:65092
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 15 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpinc1 Mutation:  4 strains or lines available
References
Original:  J:65092 Ishiguro K, et al., Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest. 2000 Oct;106(7):873-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory