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Fn1tm3Hyn
Targeted Allele Detail
Nomenclature
Symbol: Fn1tm3Hyn
Name: fibronectin 1; targeted mutation 3, Richard Hynes
MGI ID: MGI:2177826
Synonyms: FNB2, FN.B2
Gene: Fn1  Location: Chr1:71585520-71653200 bp, - strand  Genetic Position: Chr1, 36.05 cM, cytoband C1-C5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:36210
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA partial cDNA fragment corresponding to sequences of exons III7b, EIIIB and III8a replaced the genomic fragment containing these three exons. The encoded protein was not detectable in immunoprecipitations from cultures of homozygous mutant E7.5 embryos. (J:36210)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fn1 Mutation:  75 strains or lines available
References
Original:  J:36210 Georges-Labouesse EN, et al., Mesodermal development in mouse embryos mutant for fibronectin. Dev Dyn. 1996 Oct;207(2):145-56
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/19/2017
MGI 6.10
The Jackson Laboratory