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Gcktm1Tka
Targeted Allele Detail
Nomenclature
Symbol: Gcktm1Tka
Name: glucokinase; targeted mutation 1, Takashi Kadowaki
MGI ID: MGI:2177703
Synonyms: GK deficient
Gene: Gck  Location: Chr11:5900820-5950081 bp, - strand  Genetic Position: Chr11, 3.88 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:30334
Parent Cell Line:  A3-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gck Mutation:  25 strains or lines available
References
Original:  J:30334 Terauchi Y, et al., Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose. J Biol Chem. 1995 Dec 22;270(51):30253-6
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory