Myc^tm2.1Atp
Targeted Allele Detail

Summary

• Symbol: Myc^tm2.1Atp
• Name: myelocytomatosis oncogene; targeted mutation 2.1, Andreas Trumpp
• MGI ID: MGI:2177581
• Synonyms: c-myc^flox
• Gene: Myc Location: Chr15:61857240-61862223 bp, + strand Genetic Position: Chr15, 26.19 cM, cytoband D2-D3
• Alliance: Myc^tm2.1Atp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:73369
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: This heritable allele is a derivative of Myc^tm2Atp in which the frt-flanked neo cassette was removed by Flp-mediated recombination. (J:73369)

Expression

In Structures Affected by this Mutation:

10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myc Mutation: 42 strains or lines available

References

• Original: J:73369 Trumpp A, et al., c-Myc regulates mammalian body size by controlling cell number but not cell size. Nature. 2001 Dec 13;414(6865):768-73
• All: 31 reference(s)