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Skitm1Cco
Targeted Allele Detail
Summary
Symbol: Skitm1Cco
Name: ski sarcoma viral oncogene homolog (avian); targeted mutation 1, Clemencia Colmenares
MGI ID: MGI:2177555
Synonyms: ski-
Gene: Ski  Location: Chr4:155238532-155306992 bp, - strand  Genetic Position: Chr4, 86.17 cM
Alliance: Skitm1Cco page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:42573
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsInsertion of a neomycin resistance cassette into the exon 1 generated a small deletion in the coding sequence. (J:42573)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 18 assay results
In Structures Affected by this Mutation: 27 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Ski Mutation:  58 strains or lines available
References
Original:  J:42573 Berk M, et al., Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development. Genes Dev. 1997 Aug 15;11(16):2029-39
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory