Cftrtm2Bay
Targeted Allele Detail
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Symbol: |
Cftrtm2Bay |
Name: |
cystic fibrosis transmembrane conductance regulator; targeted mutation 2, Baylor College of Medicine |
MGI ID: |
MGI:2177532 |
Synonyms: |
cftrm2Bay |
Gene: |
Cftr Location: Chr6:18170686-18322767 bp, + strand Genetic Position: Chr6, 8.1 cM, cytoband A3
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Alliance: |
Cftrtm2Bay page
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Germline Transmission: |
Earliest citation of germline transmission:
J:15244
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Parent Cell Line: |
AB1 (ES Cell)
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Strain of Origin: |
129S7/SvEvBrd-Hprt1+
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Insertion
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Mutation details: An insertion vector that contained a mutated exon 3 and a neomycin selection cassette was inserted into intron 2 of the gene. The mutated exon 3 contained an oligonucleotide that introduced stop codons in all three reading frames.
(J:15244)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cftr Mutation: |
97 strains or lines available
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Original: |
J:15244 O'Neal WK, et al., A severe phenotype in mice with a duplication of exon 3 in the cystic fibrosis locus. Hum Mol Genet. 1993 Oct;2(10):1561-9 |
All: |
1 reference(s) |
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