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CrygcChl3
Chemically induced Allele Detail
Nomenclature
Symbol: CrygcChl3
Name: crystallin, gamma C; chlorambucil, exon 3
MGI ID: MGI:2176919
Gene: Crygc  Location: Chr1:65071525-65073689 bp, - strand  Genetic Position: Chr1, 32.81 cM
Mutation
origin
Strain of Origin:  (102/El x C3H/El)
Mutation
description
Allele Type:    Chemically induced (other)
Mutation:    Intragenic deletion
 
Mutation detailsA 6 bp deletion in exon 3 is causative for the cataract phenotype in this mouse. The deletion leads to the loss of two amino acids, Gly and Arg, in the fourth Greek-key motif. (J:73804)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crygc Mutation:  2 strains or lines available
References
Original:  J:73804 Graw J, et al., A 6-bp deletion in the Crygc gene leading to a nuclear and radial cataract in the mouse. Invest Ophthalmol Vis Sci. 2002 Jan;43(1):236-40
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory