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Targeted Allele Detail
Symbol: Tfap2atm1Will
Name: transcription factor AP-2, alpha; targeted mutation 1, Trevor Williams
MGI ID: MGI:2176682
Synonyms: AP-2 -, AP-2alpha-, AP-2alpha-deficient
Gene: Tfap2a  Location: Chr13:40715675-40733823 bp, - strand  Genetic Position: Chr13, 20.01 cM, cytoband A5-B1
Germline Transmission:  Earliest citation of germline transmission: J:33031
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin resistance gene replaced a geonomic fragment containing exon 6 and the first three nucleotides of exon 7, deleting sequences encoding the dimerization domain of the protein. (J:33031)
View phenotypes for all genotypes (concatenated display).
In Mice Carrying this Mutation: 11 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tfap2a Mutation:  4 strains or lines available
Original:  J:33031 Zhang J, et al., Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature. 1996 May 16;381(6579):238-41
All:  10 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 5.21
The Jackson Laboratory