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Ptpn11tm1Rbn
Targeted Allele Detail
Nomenclature
Symbol: Ptpn11tm1Rbn
Name: protein tyrosine phosphatase, non-receptor type 11; targeted mutation 1, Daniel U Rabin
MGI ID: MGI:2176526
Synonyms: syp
Gene: Ptpn11  Location: Chr5:121130533-121191397 bp, - strand  Genetic Position: Chr5, 61.72 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35137
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptpn11 Mutation:  20 strains or lines available
Notes
The ES cell line used was G1 (Bayer Corp., unpublished). This appears to have been derived from an unspecified subline of 129.

References
Original:  J:35137 Arrandale JM, et al., Insulin signaling in mice expressing reduced levels of Syp. J Biol Chem. 1996 Aug 30;271(35):21353-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory