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Transgene Detail
Symbol: Tg(CAG-cat-lacZ)11Miya
Name: transgene insertion 11, Jun-ichi Miyazaki
MGI ID: MGI:2176512
Synonyms: CAG-CAT-Z, CAG-CAT-Z11, loxP-LlacZ, Tg(ACTB-cat-lacZ)11Miya
Transgene: Tg(CAG-cat-lacZ)11Miya  Location: unknown  
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
Mutation detailsThis allele is used to detect transient expression of Cre recombinase. The transgene carries a lacZ gene downstream of a CMV enhancer and chicken beta-actin promoter and a floxed chloramphenicol acetyltransferase gene (a stuffer sequence). Upon Cre-mediated excision of the stuffer sequence, the modified allele expresses lacZ in tissues where Cre is expressed. The authors state that a single copy of the transgene was inserted and expression was observed throughout all embryonic and adult stages. (J:69322)
View phenotypes for all genotypes (concatenated display).
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
The authors state that the strain of origin is "BDF1."

Original:  J:69322 Sakai K, et al., A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem Biophys Res Commun. 1997 Aug 18;237(2):318-24
All:  52 reference(s)

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MGI 6.03
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