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Tg(CAG-cat-lacZ)11Miya
Transgene Detail
Nomenclature
Symbol: Tg(CAG-cat-lacZ)11Miya
Name: transgene insertion 11, Jun-ichi Miyazaki
MGI ID: MGI:2176512
Synonyms: CAG-CAT-Z, CAG-CAT-Z11, loxP-LlacZ, Tg(ACTB-cat-lacZ)11Miya
Transgene: Tg(CAG-cat-lacZ)11Miya  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThis allele is used to detect transient expression of Cre recombinase. The transgene carries a lacZ gene downstream of a CMV enhancer and chicken beta-actin promoter and a floxed chloramphenicol acetyltransferase gene (a stuffer sequence). Upon Cre-mediated excision of the stuffer sequence, the modified allele expresses lacZ in tissues where Cre is expressed. The authors state that a single copy of the transgene was inserted and expression was observed throughout all embryonic and adult stages. (J:69322)
Phenotypes
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
The authors state that the strain of origin is "BDF1."

References
Original:  J:69322 Sakai K, et al., A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission. Biochem Biophys Res Commun. 1997 Aug 18;237(2):318-24
All:  50 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory