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Miftm1Dvd
Targeted Allele Detail
Nomenclature
Symbol: Miftm1Dvd
Name: macrophage migration inhibitory factor; targeted mutation 1, John R David
MGI ID: MGI:2176337
Synonyms: MIF-, MIF-KO
Gene: Mif  Location: Chr10:75859353-75860250 bp, - strand  Genetic Position: Chr10, 38.59 cM, cytoband C1
BBN-induced bladder cancer is less aggressive in Miftm1Dvd/Miftm1Dvd mice than in wild type and does not invade muscle layers

Show the 2 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:52300
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mif Mutation:  5 strains or lines available
References
Original:  J:52300 Bozza M, et al., Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis. J Exp Med. 1999 Jan 18;189(2):341-6
All:  41 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory