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Cln6nclf
Spontaneous Allele Detail
Nomenclature
Symbol: Cln6nclf
Name: ceroid-lipofuscinosis, neuronal 6; neuronal ceroid lipofuscinosis
MGI ID: MGI:2159328
Synonyms: nclf
Gene: Cln6  Location: Chr9:62838785-62852006 bp, + strand  Genetic Position: Chr9, 33.89 cM
Mutation
origin
Strain of Origin:  Mixed stock
Mutation
description
Allele Type:    Spontaneous
Mutation:    Insertion
 
Mutation detailsThis allele comprises a single nucleotide insertion of a cysteine, located within a run of cysteines in exon four. The insertion produces a frameshift at amino acid 103, followed by a premature stop codon. (J:73921, J:73923)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Cln6 Mutation:  9 strains or lines available
References
Original:  J:47292 Bronson RT, et al., Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9. Am J Med Genet. 1998 May 26;77(4):289-97
All:  21 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory