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Gja1tm1Dlg
Targeted Allele Detail
Nomenclature
Symbol: Gja1tm1Dlg
Name: gap junction protein, alpha 1; targeted mutation 1, Brian R Duling
MGI ID: MGI:2159007
Synonyms: VEC Cx43 KO
Gene: Gja1  Location: Chr10:56377300-56390419 bp, + strand  Genetic Position: Chr10, 28.64 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71092
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gja1 Mutation:  35 strains or lines available
References
Original:  J:71092 Liao Y, et al., Endothelial cell-specific knockout of connexin 43 causes hypotension and bradycardia in mice. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9989-94
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory