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Oprm1tm1Lyu
Targeted Allele Detail
Summary
Symbol: Oprm1tm1Lyu
Name: opioid receptor, mu 1; targeted mutation 1, Lei Yu
MGI ID: MGI:2159002
Gene: Oprm1  Location: Chr10:6708593-6988209 bp, + strand  Genetic Position: Chr10, 1.85 cM, cytoband A2
Alliance: Oprm1tm1Lyu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:39864
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin selection cassette replaced a genomic fragment containing the first coding exon. (J:39864)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oprm1 Mutation:  53 strains or lines available
References
Original:  J:39864 Tian M, et al., Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient mice. J Exp Med. 1997 Apr 21;185(8):1517-22
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory