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Thbdtm2Rdr
Targeted Allele Detail
Nomenclature
Symbol: Thbdtm2Rdr
Name: thrombomodulin; targeted mutation 2, Robert D Rosenberg
MGI ID: MGI:2158818
Synonyms: Thbd-, TMlacZ, TMlacZ, TM-lacZ
Gene: Thbd  Location: Chr2:148404466-148408188 bp, - strand  Genetic Position: Chr2, 73.45 cM
Venous and arterial thrombi and extravascular fibrinogen deposition in the lungs of Thbdtm2Rdr/Thbdtm2Wlr Tg(Tek-cre)1Ywa/0 mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:74855
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Thbd Mutation:  1 strain or line available
References
Original:  J:74855 Weiler-Guettler H, et al., Targeting of transgene expression to the vascular endothelium of mice by homologous recombination at the thrombomodulin locus. Circ Res. 1996 Feb;78(2):180-7
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory