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Scnn1atm1Rss
Targeted Allele Detail
Nomenclature
Symbol: Scnn1atm1Rss
Name: sodium channel, nonvoltage-gated 1 alpha; targeted mutation 1, Bernard C Rossier
MGI ID: MGI:2158700
Synonyms: alphaENaC -, Scnn1atm1
Gene: Scnn1a  Location: Chr6:125320659-125344943 bp, + strand  Genetic Position: Chr6, 59.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:31762
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprtb-m3
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Scnn1a Mutation:  6 strains or lines available
References
Original:  J:31762 Hummler E, et al., Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice. Nat Genet. 1996 Mar;12(3):325-8
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory