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Hnf4atm1Dnl
Targeted Allele Detail
Nomenclature
Symbol: Hnf4atm1Dnl
Name: hepatic nuclear factor 4, alpha; targeted mutation 1, James E Darnell
MGI ID: MGI:2158682
Synonyms: HNF-4 -
Gene: Hnf4a  Location: Chr2:163506808-163572910 bp, + strand  Genetic Position: Chr2, 84.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:21129
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A genomic fragment containing exons 2 and 3 was replaced with a neomycin selection cassette. (J:21129)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hnf4a Mutation:  13 strains or lines available
References
Original:  J:21129 Chen WS, et al., Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos. Genes Dev. 1994 Oct 15;8(20):2466-77
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory