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Ptgs2tm1Unc
Targeted Allele Detail
Nomenclature
Symbol: Ptgs2tm1Unc
Name: prostaglandin-endoperoxide synthase 2; targeted mutation 1, University of North Carolina
MGI ID: MGI:2158457
Synonyms: Cox2-, COX-2-, PGHS-2-, Ptgs2tm1Smi
Gene: Ptgs2  Location: Chr1:150100124-150108010 bp, + strand  Genetic Position: Chr1, 63.84 cM, cytoband H1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:29510
Parent Cell Line:  BK4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptgs2 Mutation:  15 strains or lines available
Notes
BK4 is a subline of E14TG2a.

References
Original:  J:29510 Morham SG, et al., Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell. 1995 Nov 3;83(3):473-82
All:  111 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/15/2014
MGI 5.17
The Jackson Laboratory