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Akt2tm1.1Mbb
Targeted Allele Detail
Nomenclature
Symbol: Akt2tm1.1Mbb
Name: thymoma viral proto-oncogene 2; targeted mutation 1.1, Morris J Birnbaum
MGI ID: MGI:2158456
Synonyms: Akt2-, Akt2 KO, PKBbeta-
Gene: Akt2  Location: Chr7:27591552-27640826 bp, + strand  Genetic Position: Chr7, 15.94 cM, cytoband B1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:71491
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Akt2 Mutation:  27 strains or lines available
References
Original:  J:71491 Cho H, et al., Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta). Science. 2001 Jun 1;292(5522):1728-31
All:  51 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory