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Figlatm1Dean
Targeted Allele Detail
Nomenclature
Symbol: Figlatm1Dean
Name: folliculogenesis specific basic helix-loop-helix; targeted mutation 1, Jurrien Dean
MGI ID: MGI:2158347
Synonyms: Figalphatm, Figalphatm1Nih, Figalphatm2Nih
Gene: Figla  Location: Chr6:86016171-86020996 bp, + strand  Genetic Position: Chr6, 37.55 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:64677
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 0.8 kb genomic fragment containing the transcription and translation start sites was replaced with a neomycin selection cassette. RNAse protection assays on RNA derived from ovaries of female homozygous mice demonstrated that no detectable transcript was present. (J:64677)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 124 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Figla Mutation:  9 strains or lines available
References
Original:  J:64677 Soyal SM, et al., FIGalpha, a germ cell-specific transcription factor required for ovarian follicle formation. Development. 2000 Nov;127(21):4645-54
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory