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Ccr2tm1Mae
Targeted Allele Detail
Nomenclature
Symbol: Ccr2tm1Mae
Name: chemokine (C-C motif) receptor 2; targeted mutation 1, Nobuyo Maeda
MGI ID: MGI:2158345
Synonyms: CCR2-, Ccr2tm1Unc
Gene: Ccr2  Location: Chr9:124101950-124113557 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:44561
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccr2 Mutation:  5 strains or lines available
Notes
Phenotypic Similarity to Human Syndrome: Age-related macular degeneration (J:147328)

References
Original:  J:44561 Kuziel WA, et al., Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc Natl Acad Sci U S A. 1997 Oct 28;94(22):12053-8
All:  121 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory