Pax6^5Neu
Chemically induced Allele Detail

Summary

• Symbol: Pax6^5Neu
• Name: paired box 6; 5, Neuherberg
• MGI ID: MGI:2156817
• Synonyms: 636, ENU-636
• Gene: Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
• Alliance: Pax6^5Neu page

Mutation origin

• Strain of Origin: (102 x C3H)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation was identified as a A to T substitution in exon 6, nucleotide position 517. The resulting protein has a Arg to Stop substitution at amino acid position 119. The mutation resides in the paired box region of the protein. The linker region, homeodomain, and P/S/T domains are all deleted in the resulting protein. (J:73625)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pax6 Mutation: 90 strains or lines available

Notes

Genbank Accession ID: Y19197

References

• Original: J:21951 Favor J, The frequency of dominant cataract and recessive specific-locus mutations in mice derived from 80 or 160 mg ethylnitrosourea per kg body weight treated spermatogonia. Mutat Res. 1986 Aug;162(1):69-80
• All: 3 reference(s)