Atoh1^tm2Hzo
Targeted Allele Detail

Summary

• Symbol: Atoh1^tm2Hzo
• Name: atonal bHLH transcription factor 1; targeted mutation 2, Huda Y Zoghbi
• MGI ID: MGI:2155983
• Synonyms: Atoh1^LacZ, Math1^-, Math1^beta-Gal, Math1^lacZ, Math1/lacZ
• Gene: Atoh1 Location: Chr6:64706109-64708229 bp, + strand Genetic Position: Chr6, 30.03 cM
• Alliance: Atoh1^tm2Hzo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:60393
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ-PGK-neomycin resistance cassette replaced the coding region and placed lacZ under control of the endogenous promoter. (J:60393)

Expression

In Mice Carrying this Mutation:	534 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atoh1 Mutation: 36 strains or lines available

References

• Original: J:60393 Ben-Arie N, et al., Functional conservation of atonal and Math1 in the CNS and PNS. Development. 2000 Mar;127(5):1039-48
• All: 64 reference(s)