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Szs2C57BL/6J
QTL Variant Detail
Nomenclature
QTL variant: Szs2C57BL/6J
Name: seizure susceptibility 2; C57BL/6J
MGI ID: MGI:2155930
QTL: Szs2  Location: unknown  Genetic Position: Chr4, cM position of peak correlated region/allele: 43.34 cM
QTL Note: genome coordinates based on the marker associated with the peak LOD score
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    This allele confers increased seizure susceptibility compared to DBA/2J.
Inheritance:    Not Specified
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Notes
Szs2 is observed to interact with Szs1.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:38888

In a population of F2 mice derived from B6D2F1 x B6D2F1 hybrids the quantitative trait locus seizure severity 2 Szs2 was mapped to mouse Chromosome 4 near D4Mit19. Authors indicated that Kasz4(Szs2) maps to the same location as Asp2 (45.1 cM)

References
Original:  J:38888 Ferraro TN, et al., Mapping murine loci for seizure response to kainic acid. Mamm Genome. 1997 Mar;8(3):200-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory