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Cd3etm1Cpt
Targeted Allele Detail
Nomenclature
Symbol: Cd3etm1Cpt
Name: CD3 antigen, epsilon polypeptide; targeted mutation 1, Cox Terhorst
MGI ID: MGI:2155671
Synonyms: epsilondeltaP
Gene: Cd3e  Location: Chr9:44998743-45009590 bp, - strand  Genetic Position: Chr9, 24.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:54756
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A PGK-neomycin resistance cassette replaced the promoter region and exons 1, 2, and 3. (J:54756)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd3e Mutation:  9 strains or lines available
References
Original:  J:54756 Wang N, et al., Expression of a CD3 epsilon transgene in CD3 epsilon(null) mice does not restore CD3 gamma and delta expression but efficiently rescues T cell development from a subpopulation of prothymocytes. Int Immunol. 1998 Dec;10(12):1777-88
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory