Tg(Alb1-tTA)3123Lng
Transgene Detail
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| Symbol: |
Tg(Alb1-tTA)3123Lng |
| Name: |
transgene insertion 3123, T Jake Liang |
| MGI ID: |
MGI:2155336 |
| Transgene: |
Tg(Alb1-tTA)3123Lng Location: unknown
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| Alliance: |
Tg(Alb1-tTA)3123Lng page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: These transgenic mice express the tetracycline-inhibitable transcription factor (tTA) under the control of liver-specific mouse albumin promoter. Constitutive expression of tTA in liver makes this strain suitable for use in creating bitransgenic mice that can, by withdrawing tetracycline, inducibly express a gene of interest in the liver, when the gene of interest is under the direction of the tetracycline responsive promoter, TetOp
(J:69003)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:69003 Manickan E, et al., Conditional liver-specific expression of simian virus 40 T antigen leads to regulatable development of hepatic neoplasm in transgenic mice. J Biol Chem. 2001 Apr 27;276(17):13989-94 |
| All: |
1 reference(s) |
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Analysis Tools
