About   Help   FAQ
Thbs1tm1Hyn
Targeted Allele Detail
Nomenclature
Symbol: Thbs1tm1Hyn
Name: thrombospondin 1; targeted mutation 1, Richard Hynes
MGI ID: MGI:2154534
Synonyms: tbsp1-, Thbs1-, TSP-1, TSP-1-, TSP1-, Tsp-1KO
Gene: Thbs1  Location: Chr2:118111876-118127133 bp, + strand  Genetic Position: Chr2, 59.34 cM, cytoband F1-F3
Lordotic curvature of the spine in Thbs1tm1Hyn/Thbs1tm1Hyn mice

Show the 2 image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:46182
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (knock-out)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Thbs1 Mutation:  3 strains or lines available
References
Original:  J:46182 Lawler J, et al., Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. J Clin Invest. 1998 Mar 1;101(5):982-92
All:  78 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
04/08/2014
MGI 5.17
The Jackson Laboratory